Healthspan Assessment Panel: The Complete Guide to Optimizing Your Longevity
Introduction
When it comes to longevity, the goal is not just to live longer, but to live better. At Revolution Health, we believe the key to vibrant health is in measuring what matters most—and using that data to create personalized, proactive care. Our Healthspan Assessment Panel is the most comprehensive lab evaluation we offer. It gives an in-depth look at cardiovascular, endocrine, metabolic, thyroid, immune, and nutritional health, while also assessing inflammation, autoimmunity, and key markers of aging.
This panel is the foundation of our Core Health Assessment. It provides patients with a baseline snapshot of their health, uncovers hidden imbalances, and helps us build a personalized plan for prevention, performance, and longevity.
What Is the Healthspan Assessment Panel?
The Healthspan Assessment Panel is a comprehensive blood test that evaluates multiple systems of the body in a single draw. Unlike basic annual labs that only check a handful of markers, this panel examines dozens of biomarkers across cardiovascular, thyroid, hormone, metabolic, and immune pathways.
It measures:
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Nutritional status (vitamins, minerals, iron balance)
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Blood sugar regulation (glucose, A1c, insulin, adiponectin, leptin)
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Hormone balance (sex hormones, adrenal hormones, thyroid hormones, parathyroid function)
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Cardiovascular risk (lipids, apolipoproteins, advanced lipid particles, markers of vascular inflammation)
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Inflammation & autoimmunity (hs-CRP, homocysteine, MPO, PLAC, RF, ANA, anti-CCP3)
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Immune function (IgG, IgM, WBC differential)
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Liver & kidney function (AST, ALT, BUN, creatinine, eGFR, cystatin C, GGT, LDH)
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Muscle integrity & stress response (CK, IGF-1, BNP)
By pulling together this wide range of markers, the panel creates a whole-body health profile that helps guide preventive, functional, and longevity-focused medicine.
Complete List of Markers in the Healthspan Assessment Panel
Anemia Markers
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Ferritin
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Iron
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UIBC
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TIBC
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Transferrin
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Transferrin Saturation
Nutritional Markers
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Folate
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Vitamin D, 25-OH
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Vitamin B12
Hormones
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Estradiol
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FSH
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DHEA-S
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LH
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SHBG
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Cortisol
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Testosterone (total & free)
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Progesterone
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Parathyroid Hormone
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Prolactin
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Dihydrotestosterone
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Pregnenolone
Rheumatoid Arthritis & Autoimmunity
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RF IgM
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Anti-CCP3 IgG and IgA
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ANA IFA Panel
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hs-CRP
Thyroid Panel
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T3
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T4
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Free T3
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Free T4
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TSH
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Anti-TPO
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Reverse T3
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Anti-TG
CBC, Differential & Platelets
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WBC, RBC, Hemoglobin, Hematocrit
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MCV, MCH, MCHC, RDW-SD, RDW-CV
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Platelet count
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Neutrophils, lymphocytes, monocytes, eosinophils, basophils
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Immature granulocytes
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MPV, nucleated RBC count & %
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Reticulocytes (count, %, IRF, hemoglobin)
Comprehensive Metabolic Panel (CMP)
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Sodium, potassium, chloride, CO₂
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Glucose (renal)
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BUN, creatinine, eGFR (general & African American), BUN/creatinine ratio
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Calcium, albumin, ALT, AST, bilirubin (total), protein (total), alkaline phosphatase, serum osmolality
Lipids & Cardiovascular Markers
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Total cholesterol, LDL, HDL, triglycerides, cholesterol/HDL ratio
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LDL Direct
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Apolipoproteins: Apo A-1, Apo B, Apo B:Apo A-1
Inflammation Markers
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PLAC
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Homocysteine
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ox-LDL
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MPO
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hs-CRP
Myocardial Stress
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NT-proBNP
Advanced Lipoprotein Markers
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sdLDL
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Lp(a)
Glycemic Control
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Glucose (diabetes)
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Hemoglobin A1C
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Glycated Serum Protein
Insulin Resistance & Beta Cell Function
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Adiponectin
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Ferritin
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Insulin
Other Functional Markers
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Total IgG
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Total IgM
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Total CK
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Uric Acid
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Human IGF-1
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Cystatin C
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GGT
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LDH
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Leptin
Why Should Someone Do the Healthspan Assessment Panel?
1. Preventive Medicine at Its Best
This panel doesn’t just detect disease—it identifies early imbalances that could lead to disease. For example, homocysteine and ox-LDL can indicate vascular stress long before heart disease develops, while markers like Reverse T3 reveal thyroid dysfunction even when TSH looks “normal.”
2. Comprehensive View of Health
Instead of piecing together results from multiple labs, this test brings everything under one roof. It covers cardiovascular, endocrine, metabolic, immune, and inflammatory pathways together, offering a complete health snapshot.
3. Personalized Longevity Roadmap
Everyone ages differently. By testing markers tied to aging, inflammation, and metabolic health, the panel helps create personalized strategies for healthspan extension, from nutrition to hormone optimization to advanced therapies.
4. Tracking Progress Over Time
This panel is not just for baseline testing. Repeating it annually (or after lifestyle interventions) shows how changes in diet, supplements, exercise, and medications are working. It transforms guesswork into measurable progress.
5. Managing Complex Conditions
For patients with autoimmune disease, fatigue, thyroid dysfunction, cardiovascular risk, or unexplained symptoms, the Healthspan Assessment provides data-driven insights that standard labs often miss.
How the Healthspan Assessment Helps Us Optimize Health
Cardiovascular Health
By analyzing advanced lipids (sdLDL, Apo B:Apo A-1 ratio) and vascular inflammation (MPO, PLAC, ox-LDL), we can detect hidden cardiovascular risk and intervene early.
Hormonal Balance
Sex hormones, adrenal hormones, thyroid hormones, and parathyroid hormones are evaluated in depth. This helps guide hormone replacement therapy, fertility support, adrenal optimization, and thyroid management.
Metabolic & Blood Sugar Control
Insulin, adiponectin, leptin, and A1c provide insight into insulin resistance, metabolic syndrome, and diabetes prevention. These markers allow for targeted nutritional and peptide therapy interventions.
Nutritional & Immune Status
Markers like B12, folate, vitamin D, IgG, and IgM reveal nutritional deficiencies and immune imbalances. Optimizing these supports energy, cognition, and immune resilience.
Inflammation & Autoimmunity
From hs-CRP to ANA to anti-CCP3, this panel catches hidden inflammation and autoimmune activation—critical for patients struggling with fatigue, joint pain, or chronic illness.
Organ Function & Longevity
Liver (AST, ALT, GGT), kidney (eGFR, cystatin C), and tissue damage markers (CK, LDH) provide a window into long-term organ health, ensuring that longevity strategies are both safe and effective.
Who Benefits Most from the Healthspan Assessment Panel?
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Anyone seeking preventive care: establishes a baseline and identifies early risks.
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Patients with chronic conditions: autoimmune, thyroid, cardiovascular, or metabolic disease.
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Those pursuing longevity and performance medicine: optimizes nutrition, hormones, and inflammation.
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Individuals starting new programs: diet, supplements, peptides, or exercise—so they can measure effectiveness.
Conclusion
The Healthspan Assessment Panel is more than just a lab test—it’s a roadmap for vibrant health and longevity. By bringing together cardiovascular, endocrine, metabolic, immune, nutritional, and inflammatory markers, it provides the most complete view of health available today.
This test allows us to move beyond symptom management and into true prevention, performance, and personalized medicine. Whether you’re trying to prevent disease, optimize aging, or simply live better, the Healthspan Assessment Panel is one of the most powerful tools available to guide your health journey.