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May 11, 2025

Thymosin Alpha 1 Peptide (TA1): Immunity, Antiviral & Longevity Benefits

Thymosin Alpha 1 is a powerful immune-boosting peptide shown to improve antiviral defense, regulate inflammation, and support overall resilience.

Thymosin Alpha-1 (TA-1) Peptide for immune support

Thymosin Alpha 1 (TA-1): Immune-Boosting Peptide Therapy You Should Know About

Thymosin Alpha 1 (TA-1) is a naturally occurring peptide with powerful immune-modulating and antiviral properties. Originally isolated from the thymus gland, TA-1 has been used in clinical practice for decades to support immune resilience, especially in individuals with chronic infections, immune suppression, or inflammation.

At Revolution Health & Wellness, we use physician-supervised, research-grade TA-1 sourced from an FDA-regulated facility. It's important to understand how this peptide works—and how to optimize its effects, including one essential nutrient you might be missing: zinc.

What Is Thymosin Alpha 1?

Thymosin Alpha 1 is a 28-amino acid peptide fragment derived from prothymosin alpha, a protein involved in regulating the immune system. It plays a crucial role in:

  • Promoting the maturation and differentiation of T cells

  • Enhancing the activity of natural killer (NK) cells

  • Modulating inflammatory responses

  • Improving immune surveillance

  • Supporting antiviral and antibacterial defenses

Because of these effects, TA-1 is used in conditions ranging from viral infections (like hepatitis B/C or Lyme) to cancer, autoimmune disorders, and even as an adjuvant during vaccine administration.

Conditions Where TA-1 May Be Helpful

Research and clinical experience suggest benefits of TA-1 for:

  • Chronic viral infections (EBV, CMV, HSV, HPV, Hepatitis B & C)

  • Acute infections, including support during respiratory viral illnesses

  • Immune suppression, especially in cancer or chemotherapy patients

  • Autoimmune disease modulation

  • Persistent Lyme disease and coinfections

  • Post-viral fatigue syndromes, including long COVID

How Is Thymosin Alpha 1 Administered?

TA-1 is typically administered as a subcutaneous injection (similar to an insulin shot) twice weekly or as directed by your physician. The standard vial contains 10mg of TA-1. To prepare the vial, we add 0.4mL of bacteriostatic or sterile water, yielding a 0.25mg/unit concentration. The recommended dose is:

  • 2.5mg (10 units) to 5mg (20 units) subcutaneously

  • Two days per week (e.g., Monday and Thursday)

Protocols vary depending on the clinical goal. For general immune support, lower doses may be sufficient, while chronic infections or cancer support may warrant higher dosing under physician supervision.

These protocols are for informational or educational purposes only. Any TA-1 dosing should be under the direct supervision of a licensed physician trained in peptide therapy. 

Why Zinc Is Essential for Thymosin Alpha 1 to Work

While TA-1 is a potent immune modulator on its own, its effectiveness depends on adequate zinc status. Zinc is a critical cofactor in over 300 enzymatic reactions, many of which are involved in immunity and inflammation control. Importantly:

  • TA-1 requires zinc to activate T cells and natural killer cells

  • Zinc deficiency may blunt the benefits of TA-1, especially in chronically ill or older individuals

  • Zinc enhances immune signaling pathways that TA-1 directly supports

How to Know if You're Zinc Deficient

Many people assume their zinc levels are fine, but research shows that subclinical zinc deficiency is common, especially in those with gut issues, poor diets, or chronic inflammation.

We recommend testing with a Micronutrient Panel that includes RBC Zinc levels, as this provides a more accurate picture of intracellular zinc stores. You can learn more about this testing here:

Alternatively, a basic serum zinc test can be ordered through conventional labs, but it is less reliable for detecting subtle deficiencies.

What Zinc Supplement Do We Recommend?

For optimal compatibility and absorption, we recommend Zinc Glycinate, a chelated form that is easy on the stomach and well tolerated even at higher doses. You can purchase our recommended zinc supplement here:

Typical dosing is 1 capsule daily with food, but this may vary depending on your test results and medical history. We can guide you on the optimal dose during your visit.

What Makes Our TA-1 Different?

At Revolution Health & Wellness, all peptides—including TA-1—are:

  • Sourced from FDA-monitored manufacturers

  • Intended for physician-supervised use only

  • Tested for sterility and purity

  • Not compounded or obtained from research pharmacies

This ensures you get pharmaceutical-grade quality you can trust. TA-1 is not FDA-approved for all uses and is prescribed based on current research, clinical experience, and individual needs.

Who Should Consider TA-1?

Thymosin Alpha 1 may be an excellent choice if you:

  • Get sick often or have poor immune recovery

  • Struggle with chronic infections or viral reactivations

  • Have a suppressed or overactive immune system

  • Want to support immune health while traveling or during cold/flu season

  • Are recovering from long COVID or persistent fatigue syndromes

  • Are undergoing treatment for cancer or other chronic diseases

How Long Should I Take TA-1?

The ideal duration depends on your condition:

  • Immune support: 4–12 weeks, often seasonally

  • Chronic illness: 3–6 months or longer

  • Cancer or immune suppression: under continuous medical supervision

In many cases, TA-1 is pulsed intermittently throughout the year to maintain resilience.

Can TA-1 Be Combined With Other Peptides?

Yes. TA-1 is often part of comprehensive immune protocols and can be safely combined with:

  • LL-37 (for antimicrobial support)

  • KPV (for inflammation control)

  • BPC-157 (for gut and immune healing)

  • GHK-Cu (for tissue regeneration)

These combinations can be tailored to your unique needs and goals.

Summary: Key Takeaways

  • Thymosin Alpha 1 (TA-1) is a powerful immune-boosting peptide used in a wide range of chronic and acute illnesses.

  • It enhances T cell and NK cell activity, supports antiviral defense, and helps regulate inflammation.

  • Zinc is required for TA-1 to work efficiently. We recommend testing RBC Zinc levels or supplementing with Zinc Glycinate.

  • TA-1 is best used under the supervision of a physician and as part of an integrated care plan.

  • Revolution Health offers only physician-grade, peptides manufactured in an FDA-monitored facility, including TA-1.

Ready to Start TA-1 Therapy?

If you're struggling with immune dysfunction, chronic illness, or just want to optimize your defenses, Thymosin Alpha 1 may be the missing piece. Contact us today to schedule a consultation and create a personalized peptide plan—including appropriate zinc support—to get the most from this remarkable therapy.