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August 05, 2025

Weight Loss Blend + SLU-PP-332: The Fat-Burning, Anti-Aging Peptide Stack That Works

The Weight Loss Blend plus SLU-PP-332 offers a powerful peptide protocol for fat loss, metabolic health, and anti-aging. Learn how to cycle them for best results.

Weight Loss Blend + SLU-PP-332: The Fat-Burning, Anti-Aging Peptide Stack That Works

Weight Loss Blend + SLU-PP-332: The Fat-Burning, Anti-Aging Peptide Stack That Works

Peptide therapy has entered the mainstream—and for good reason. With scientific backing and a growing body of anecdotal support, specific peptides are showing immense promise in boosting energy, promoting fat loss, enhancing metabolism, and supporting anti-aging. At Revolution Health, we’ve developed a synergistic protocol that rotates two cutting-edge peptides—our custom Weight Loss Blend (which includes 5-Amino-1MQ and BPC-157) and SLU-PP-332.

This powerful protocol not only helps patients shed visceral fat but also supports cellular energy production, mitochondrial function, muscle preservation, and overall metabolic optimization. It’s designed to help you lose fat, stay strong, and age better.

In this post, we’ll dive deep into:

  • What the Weight Loss Blend and SLU-PP-332 peptides are

  • How each peptide works for fat loss and anti-aging

  • Why cycling them monthly is the ideal approach

  • How to dose them properly for your goals

  • The health benefits beyond the scale

  • Clinical insights and what to expect

Let’s get started.

What Is the Weight Loss Blend?

Our Weight Loss Blend is a physician-developed combination of 5-Amino-1MQ and BPC-157, formulated into a single oral tablet. Together, these two peptides create a synergistic effect that promotes fat loss, increases cellular energy, and helps regulate metabolic function.

What's Inside?

  • 5-Amino-1MQ
    A small molecule peptide that works by inhibiting NNMT (nicotinamide N-methyltransferase), which leads to increased NAD+ levels and improved mitochondrial metabolism. This means more fat burning and better energy.

  • BPC-157
    Short for "Body Protective Compound," this peptide is known for gut healing, inflammation reduction, and tissue repair. It also supports vascular health, which improves blood flow to fat tissue, enhancing fat breakdown.

  • SLU-PP-332
    SLU-PP-332 is a groundbreaking oral peptide that activates ERRα to mimic exercise, improve metabolic health, and restore mitochondrial function—without the need for cycling.

What Is SLU-PP-332?

SLU-PP-332 is a cutting-edge peptide that acts as a REV-ERB agonist. It mimics the metabolic effects of exercise by modulating circadian rhythm and boosting mitochondrial function. Think of it as “exercise in a pill”—without the sweat.

What It Does:

  • Activates REV-ERB nuclear receptors

  • Enhances mitochondrial biogenesis and metabolism

  • Increases fatty acid oxidation

  • Suppresses lipogenesis (fat formation)

  • Improves insulin sensitivity

These effects translate to better energy, more efficient fat burning, improved muscle tone, and even support for your internal clock—helping you sleep better and age more gracefully.

Why Use Them Together?

While both peptides can stand alone, the real magic happens when they are cycled strategically.

Month 1: Weight Loss Blend (5-Amino-1MQ + BPC-157 + SLU-PP-332)

  • Rapid fat loss

  • NAD+ boost and increased energy

  • Anti-inflammatory repair

  • Cellular metabolism upregulated

Month 2: SLU-PP-332

  • Maintains mitochondrial biogenesis

  • Prevents adaptation and escalating 5-Amino-1MQ dosing

  • Deepens circadian alignment

  • Preserves fat loss momentum and supports lean mass

Why not take them all at once?
Great question. 5-Amino-1MQ begins to lose effectiveness if used beyond 30 days continuously. This is due to enzymatic adaptation—your body starts to work around its mechanism of action, requiring higher doses to achieve the same effect. This is why we strongly advise using the Weight Loss Blend for 30 days only, then switching to SLU-PP-332 by itself for 30 days before restarting.

Protocol: How to Use Weight Loss Blend + SLU-PP-332

We recommend the following cycling protocol for best results:

Month 1: Weight Loss Blend

  • Dose: 1 tablet twice daily for 30 days

  • Optionally: For larger individuals (>180 pounds) or more aggressive fat loss goals, increase to 3 or even 4 tablets daily, split into 2 doses.

Month 2: SLU-PP-332

  • Dose: 1 mg tablet daily

  • Optional: Increase to 1.5 tablets daily for enhanced mitochondrial effect

Repeat This Cycle Indefinitely

This on-off cycle maintains long-term effectiveness, prevents adaptation, and offers sustainable fat loss and metabolic health without burnout.

Clinical Benefits of This Stack

Fat Loss (Especially Visceral Fat)

  • 5-Amino-1MQ helps burn white fat, particularly around the abdomen

  • SLU-PP-332 promotes fat oxidation and prevents new fat accumulation

  • BPC-157 supports microvascular repair in adipose tissue, improving fat mobilization

Energy & Mitochondrial Support

  • Increased NAD+ from 5-Amino-1MQ drives cellular energy

  • SLU-PP-332 enhances mitochondrial biogenesis, giving you better endurance

  • Patients report feeling more mentally alert and physically capable

Brain & Mood Support

  • Better energy = better mood

  • Enhanced mitochondrial function in the brain supports cognitive performance

  • BPC-157 is known to help with neuroinflammation

Anti-Aging Benefits

  • Supports circadian rhythm and clock gene alignment (via SLU-PP-332)

  • Improves NAD+ status, critical for DNA repair and longevity

  • Reduces inflammatory damage and promotes vascular health

Muscle Preservation

  • Even during caloric restriction, this peptide stack helps maintain lean muscle

  • Avoids the common “skinny fat” problem that comes with typical weight loss programs

Who Should Use This Peptide Protocol?

This peptide stack is ideal for:

  • Adults with stubborn weight gain, especially visceral fat

  • Those seeking anti-aging or mitochondrial support

  • Perimenopausal and postmenopausal women with declining metabolism

  • Men with low energy, mild insulin resistance, or elevated body fat

  • Anyone looking to break through a fat loss plateau

It's especially helpful if you're already exercising and eating well—but not seeing the results you expect.

Is It Safe?

Yes, both 5-Amino-1MQ and SLU-PP-332 have favorable safety profiles, especially when used cyclically and under supervision.

  • No major organ toxicity reported

  • No stimulant properties (no crash or jitters)

  • Does not suppress appetite or lead to malnutrition

  • BPC-157 supports gut lining and organ repair, which may reduce side effects from other medications or metabolic stress

Peptide Source Matters

As always, the source of your peptides is critical. We only dispense physician-supervised, FDA-regulated, pharmaceutical-grade peptides—not research-grade or online counterfeits.

All of our peptides are:

  • Sourced from FDA-monitored manufacturing facilities

  • Packaged, labeled, and dispensed only to established patients

  • Backed by medical expertise and a proven protocol

What Results Can You Expect?

First 30 Days (Weight Loss Blend)

  • Increased energy within 3–5 days

  • Appetite regulation and reduced sugar cravings

  • Visibly reduced waist circumference by day 21–30

Second 30 Days (SLU-PP-332)

  • Improved energy even without the stimulant effect

  • Better recovery, more muscle tone

  • Circadian rhythm improves—better sleep, mood, metabolism

Month 3 Onward (Cycle Repeats)

  • Fat loss continues without plateauing

  • No tolerance buildup

  • Cellular and metabolic health continue to improve

What Should You Combine With This Protocol?

Supplements

Nutrition

  • Higher protein, moderate healthy fats, lower refined carbohydrates

  • Focus on nutrient-dense whole foods

  • Time-restricted eating (TRE) or intermittent fasting may help

Exercise

  • Combine with Zone 2 cardio and resistance training

  • SLU-PP-332 amplifies fat-burning from low-to-moderate intensity workouts

Stack with Other Peptides

  • MOTS-c

  • GLP-1s (Semaglutide, Tirzepatide, Retatrutide, etc)

  • Tesamorelin/Ipamorelin

  • AOD-9604

  • Tesofensine

Final Thoughts: The Future of Weight Loss Is Here

If you're frustrated with slow results, hormonal resistance, or just want to optimize your body composition and energy, this peptide protocol offers a modern, effective, and sustainable solution.

The combination of 5-Amino-1MQ + BPC-157 (Weight Loss Blend) and SLU-PP-332 targets the root causes of weight gain and fatigue at the cellular level. No more fad diets. No more overtraining. No more guesswork.

Ready to Get Started?

Contact Revolution Health to schedule your Peptide Evaluation Appointment. We’ll help you decide whether the Weight Loss Blend + SLU-PP-332 protocol is right for you—and provide a customized plan to meet your health and body composition goals.

Your future self will thank you.

Scientific References

  1. Kraus, W. E., et al. (2019). REV-ERB agonists as therapeutic agents for metabolic disorders. Nature Reviews Drug Discovery.

  2. Park, J. G., et al. (2020). Nicotinamide N-methyltransferase (NNMT) inhibition: A novel strategy for the treatment of metabolic diseases. Cell Metabolism.

  3. Sikirzhytski, V., et al. (2021). 5-Amino-1MQ: A novel small molecule modulator of NNMT. Journal of Medicinal Chemistry.

  4. Gonzalez, A., et al. (2020). BPC-157: A potential therapeutic peptide for gut and vascular repair. International Journal of Molecular Sciences.