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June 23, 2025

Hormone Zoomer Lab Test: Urinary Hormone and Endocrine Disruptor Insights

Discover how the Hormone Zoomer identifies hormone imbalances, toxic exposures, and oxidative stress through a urine-based functional lab panel.

hormone zoomer urine lab test

Hormone Zoomer Lab Test: Advanced Urinary Insight into Hormones, Toxins, and Metabolism

Hormones regulate energy, metabolism, sleep, mood, reproductive health, and much more. When hormonal imbalances develop, they often go undetected or are evaluated with limited testing. The Hormone Zoomer is a comprehensive, urine-based test designed to evaluate hormone metabolism, diurnal cortisol rhythm, melatonin output, oxidative stress, and even exposure to environmental toxins known to act as endocrine disruptors.

This test delivers far more than just a snapshot of hormone levels. It reveals how hormones are processed, how toxins may be disrupting their activity, and how oxidative stress may be impairing cellular function. If you're experiencing unexplained fatigue, weight gain, hormonal symptoms, sleep issues, or metabolic dysfunction, the Hormone Zoomer may be a critical step toward finding answers.

What Makes the Hormone Zoomer Unique?

Unlike saliva or blood spot tests that offer static or isolated data points, the Hormone Zoomer uses multiple urine collections throughout the day to evaluate:

  • Hormone production

  • Hormone metabolism and detoxification

  • Daily cortisol and melatonin rhythm

  • Oxidative DNA damage

  • Endocrine disruptor burden

  • Bone turnover markers

This dynamic view offers providers and patients a powerful tool for tailoring personalized treatments based on real-time functional patterns.

What the Hormone Zoomer Measures

Sex Hormones and Metabolites

  • Estradiol (E2)

  • Estrone (E1)

  • Estriol (E3)

  • Progesterone metabolites: β-Pregnanediol, α-Pregnanediol, Allopregnanolone, 3α-Dihydroprogesterone, 20α-Dihydroprogesterone

  • Estrogen detox metabolites: 2-OH E1, 4-OH E1, 16α-OH E1, 2-MeO E1, 4-MeO E1, 2-OH E2, 4-OH E2, 2-MeO E2, 4-MeO E2

  • Total Estrogen

Androgens and Metabolites

  • Testosterone

  • Epi-Testosterone

  • 5α-DHT (Dihydrotestosterone)

  • 5α,3α-Androstanediol

  • 5β-Androstanediol

  • Androstenedione

  • Androsterone

  • Etiocholanolone

Adrenal Hormones and Metabolites

  • DHEA and DHEA-S

  • Total Cortisol

  • Total Cortisone

  • β-Tetrahydrocortisol (THF), α-THF, β-Tetrahydrocortisone (THE)

  • Metabolized Cortisol = THF + THE

Diurnal Cortisol & Cortisone Rhythm

  • Free Cortisol: 4 points (morning 1 & 2, evening, night)

  • Free Cortisone: 4 points

  • Pooled Free Cortisol & Cortisone

Melatonin Rhythm

  • Melatonin measured at 4 time points to assess circadian regulation

Endocrine Disruptors

Measures environmental chemicals known to disrupt hormonal pathways:

  • BPA (Bisphenol A)

  • Atrazine

  • Glyphosate

  • Phthalates (multiple forms)

  • Parabens (methyl-, ethyl-, butyl-, propyl-)

  • Triclosan

  • Perchlorate

Bone Health Markers

  • Deoxypyridinoline (DPD)

  • Pyridinoline (PYD)

Oxidative Stress

  • 8-Hydroxy-2-deoxyguanosine (8OHdG), a marker of DNA damage

Key Advantages of the Hormone Zoomer

1. Comprehensive Hormone Analysis

It measures both parent hormones and their metabolites, allowing you to see not only how much hormone your body produces, but how it processes and detoxifies those hormones. This is essential for identifying estrogen dominance, poor methylation, or androgen excess.

2. Toxin and Endocrine Disruptor Exposure

Exposure to chemicals like BPA, phthalates, and parabens can interfere with hormonal signaling. The Hormone Zoomer uniquely includes these compounds, helping explain hormone resistance or dysfunction.

3. Circadian Cortisol & Melatonin Profiling

Four-point cortisol and melatonin assessment helps diagnose adrenal fatigue, HPA axis dysfunction, and circadian rhythm disorders that can affect sleep, mood, and metabolism.

4. Bone & DNA Integrity Insight

DPD and PYD provide early clues about bone resorption, and 8-OHdG reflects oxidative damage to DNA, useful for anti-aging, detox, and mitochondrial protocols.

When to Use the Hormone Zoomer

This test is especially helpful for patients with:

  • Chronic fatigue or burnout

  • Weight gain resistant to diet and exercise

  • Estrogen dominance symptoms (PMS, fibroids, breast tenderness)

  • PCOS and androgen excess

  • Infertility or subfertility

  • Perimenopausal or menopausal transition

  • Insomnia or circadian rhythm disorders

  • Suspected toxic burden or exposure to endocrine-disrupting chemicals

  • Need for adrenal rhythm mapping

Sample Collection and Turnaround

  • Collection: 4 urine samples over the course of a single day

  • Method: Midstream collection into included containers, then shipped back to the lab

  • Turnaround: Results typically available in 10–14 business days

Clinical Application and Interpretation

Results from the Hormone Zoomer allow clinicians to:

  • Customize hormone replacement therapy

  • Determine need for estrogen detox support (DIM, Calcium-D-glucarate, methyl donors)

  • Identify hidden sources of stress and adrenal dysfunction

  • Recommend detoxification protocols for endocrine disruptors

  • Support mitochondrial health and DNA repair

Final Thoughts

The Hormone Zoomer is a state-of-the-art tool for evaluating endocrine, metabolic, toxic, and oxidative influences on health. Unlike traditional hormone testing, it provides the "why" behind hormonal symptoms by integrating detox, adrenal rhythm, and toxic burden into a single comprehensive panel.

If you're struggling with unexplained symptoms or want to proactively optimize your hormone health, the Hormone Zoomer offers an unparalleled lens into your body's most vital regulatory systems.

Want help interpreting your Hormone Zoomer results or deciding if this test is right for you? Contact our clinic to schedule a functional medicine consultation.