Revolution Advanced Hormone Panel: The Most Complete Look at Your Hormones
Introduction
Hormones control nearly every function in the human body—from metabolism and body composition to mood, energy, sleep, fertility, and long-term health. When your hormones are out of balance, symptoms can appear gradually, often brushed off as “normal aging” or stress, when in reality they are signs that your endocrine system needs attention.
The Revolution Advanced Hormone Panel provides one of the most comprehensive assessments available. This test goes far beyond basic labs, measuring not only sex hormones like testosterone and estradiol, but also key regulators such as cortisol, DHEA-S, prolactin, parathyroid hormone, and pregnenolone. With this expanded view, clinicians can uncover root causes of hormonal imbalances and design personalized treatment plans.
We order this panel through Vibrant Wellness, a trusted clinical lab specializing in advanced functional testing. Let’s take a detailed look at what’s included, why each marker matters, and how this testing can change the way you approach your health.
Why Comprehensive Hormone Testing Matters
Most conventional hormone panels only scratch the surface. For example, a primary care physician may check TSH for thyroid health or total testosterone in men, but rarely orders a complete evaluation. This leaves gaps in understanding how hormones interact as a network.
The Revolution Advanced Hormone Panel solves this by testing multiple hormones and binding proteins at once, allowing providers to:
-
See the full picture rather than isolated values
-
Identify subtle imbalances before they turn into major health problems
-
Correlate symptoms with objective data for targeted treatment
-
Track progress with precise before-and-after comparisons
Hormones Measured in the Revolution Advanced Hormone Panel
1. Testosterone (Free & Total)
Testosterone is critical for energy, strength, muscle growth, bone density, libido, and cognitive function.
-
Total Testosterone measures the overall amount circulating in the bloodstream.
-
Free Testosterone represents the fraction not bound to proteins like SHBG or albumin—this is the bioavailable portion that directly acts on cells.
Low testosterone can cause fatigue, decreased motivation, muscle loss, erectile dysfunction, and mood swings. Too much testosterone, on the other hand, can trigger acne, hair loss, aggression, and cardiovascular strain. Both men and women benefit from optimal levels, though ideal ranges differ.
2. Sex Hormone Binding Globulin (SHBG)
SHBG is a protein that binds tightly to testosterone and estradiol, making them inactive. High SHBG can reduce free testosterone, even if total testosterone looks normal. Low SHBG may increase free testosterone but can also signal insulin resistance, liver disease, or thyroid dysfunction.
Measuring SHBG helps interpret testosterone results more accurately and is crucial for both men and women struggling with hormone-related symptoms.
3. Estradiol (E2)
Estradiol is the most potent form of estrogen. While it’s often associated with women’s health, it also plays key roles in men.
-
In women, estradiol regulates the menstrual cycle, fertility, bone density, and cardiovascular protection.
-
In men, it supports brain function, libido, and joint health but must be kept in balance with testosterone.
Low estradiol in women can cause hot flashes, night sweats, vaginal dryness, and osteoporosis. High estradiol in men can lead to gynecomastia, fat gain, and low libido.
4. Follicle-Stimulating Hormone (FSH)
FSH is produced by the pituitary gland and stimulates egg development in women and sperm production in men.
-
High FSH in women often indicates reduced ovarian reserve or menopause.
-
In men, elevated FSH suggests testicular dysfunction.
-
Low FSH can mean pituitary or hypothalamic suppression.
Together with LH, FSH provides a window into reproductive health.
5. Dehydroepiandrosterone Sulfate (DHEA-S)
DHEA-S is a precursor hormone made by the adrenal glands. It can be converted into testosterone and estrogens, and it also has independent benefits for mood, immunity, and aging.
-
Low DHEA-S is associated with adrenal fatigue, stress, chronic illness, and aging.
-
High levels may be seen in polycystic ovary syndrome (PCOS) or adrenal tumors.
Because it reflects long-term adrenal function, DHEA-S is one of the most useful hormones to assess overall resilience.
6. Luteinizing Hormone (LH)
LH stimulates ovulation in women and testosterone production in men.
-
In women, LH works in balance with FSH. Abnormal ratios may suggest PCOS.
-
In men, low LH with low testosterone points to pituitary suppression, while high LH with low testosterone indicates testicular failure.
Measuring LH alongside FSH helps determine whether hormone imbalances originate in the brain or gonads.
7. Cortisol
Known as the “stress hormone,” cortisol is produced by the adrenal glands. It regulates energy, inflammation, and circadian rhythms.
-
Chronic stress can lead to high cortisol, contributing to weight gain, high blood pressure, and anxiety.
-
Low cortisol may indicate adrenal exhaustion, leading to fatigue, dizziness, and immune dysfunction.
Testing cortisol as part of this panel provides critical insight into how stress affects your hormonal network.
8. Progesterone
Progesterone balances estrogen and plays a vital role in fertility, pregnancy, sleep, and mood.
-
In women, low progesterone can cause irregular cycles, PMS, anxiety, and miscarriage risk.
-
In men, small amounts are needed for healthy testosterone balance and brain function.
Progesterone also acts as a calming, GABA-supporting hormone, which is why low levels often show up as anxiety and insomnia.
9. Parathyroid Hormone (PTH)
PTH regulates calcium and phosphorus balance, essential for bone health and neuromuscular function.
-
High PTH can result from vitamin D deficiency, kidney disease, or parathyroid disorders.
-
Low PTH may cause dangerous drops in calcium, leading to muscle cramps or seizures.
Including PTH in this panel allows for a more holistic view of bone and mineral health.
10. Prolactin
Prolactin is best known for stimulating milk production in women after childbirth, but it also affects reproductive function in both sexes.
-
High prolactin in men can suppress testosterone, cause erectile dysfunction, and lead to infertility.
-
In women, excess prolactin may cause irregular periods or galactorrhea (milk production without pregnancy).
Because prolactin imbalances often signal pituitary issues, it’s a critical marker to include.
11. Dihydrotestosterone (DHT)
DHT is a potent metabolite of testosterone, responsible for many of its effects on hair growth, skin, and prostate health.
-
High DHT levels are linked to male pattern baldness, acne, and prostate enlargement.
-
Low DHT may blunt the beneficial effects of testosterone on strength and vitality.
Testing DHT alongside testosterone provides a deeper understanding of androgen metabolism.
12. Pregnenolone
Pregnenolone is often called the “mother hormone” because it serves as a precursor to nearly all steroid hormones, including cortisol, progesterone, testosterone, and estrogen.
Low pregnenolone may contribute to fatigue, poor memory, low resilience to stress, and decreased hormone synthesis overall. Measuring it can identify upstream deficiencies in hormone production.
13. Albumin
Albumin is a major protein in the blood that binds hormones, nutrients, and medications.
-
It influences how much testosterone is free versus bound.
-
Low albumin can reflect poor liver function, malnutrition, or chronic disease.
Including albumin ensures that free and bioavailable hormone levels are interpreted accurately.
Who Should Consider the Revolution Advanced Hormone Panel?
This panel is valuable for anyone experiencing symptoms of hormonal imbalance, including:
-
Fatigue, brain fog, or mood swings
-
Unexplained weight gain or difficulty losing fat
-
Low libido or sexual dysfunction
-
Irregular or painful menstrual cycles
-
Hair thinning or loss
-
Hot flashes, night sweats, or perimenopause symptoms
-
Difficulty building or maintaining muscle
-
Signs of adrenal fatigue (low energy, poor stress tolerance)
-
Osteopenia, osteoporosis, or bone pain
It is also useful for those who want a baseline health assessment, particularly athletes, people starting hormone replacement therapy (HRT), or patients with complex metabolic conditions.
The Advantage of Ordering Through Vibrant Wellness
We partner with Vibrant Wellness, a leading functional medicine lab, to deliver advanced and highly accurate hormone testing. Vibrant uses cutting-edge technology to ensure precision and reproducibility of results, giving you confidence that the numbers reflect your true biology.
Results are then reviewed with your provider at Revolution Health, where a personalized plan is created. This may include:
-
Lifestyle interventions (diet, sleep, stress management)
-
Nutritional supplementation
-
Bioidentical hormone replacement therapy (BHRT)
-
Peptide therapy for hormonal support
-
Ongoing monitoring to track progress
How the Testing Process Works
-
Consultation – Discuss your symptoms and goals with your provider.
-
Lab Draw – Blood sample is collected and shipped to Vibrant Wellness.
-
Results Review – Within about a week, results are available for review.
-
Treatment Plan – Your provider explains what the numbers mean and recommends a personalized program.
-
Follow-Up – Periodic re-testing ensures that your plan is working and hormones are optimized.
Conclusion
The Revolution Advanced Hormone Panel offers one of the most complete hormone evaluations available today. By measuring testosterone (free and total), SHBG, estradiol, FSH, DHEA-S, LH, cortisol, progesterone, parathyroid hormone, prolactin, DHT, pregnenolone, and albumin, this test reveals the full picture of your hormonal health.
Whether you’re struggling with fatigue, weight changes, sexual dysfunction, mood swings, or simply want to optimize your long-term wellness, this panel provides the data needed to take control of your health.
At Revolution Health, we believe knowledge is power. With advanced testing through Vibrant Wellness and personalized treatment strategies, you can restore balance, reclaim vitality, and live life at your best.