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August 24, 2025

What to Expect After Testosterone Pellet Insertion for Men | Revolution Health

Testosterone pellet therapy provides steady hormone balance for men without daily hassle. Learn what to expect after insertion, common temporary side effects, aftercare instructions, the importance of follow-up labs at 4 weeks, and why most men need repeat pellets every 4–5 months.

What to Expect After Hormone Pellet Insertion: A Guide for Men

Introduction

Hormone pellet therapy is one of the most reliable and effective ways for men to restore healthy testosterone levels. Unlike daily gels or weekly injections, pellets provide a steady release of testosterone for months at a time. This not only simplifies therapy but also ensures more consistent symptom relief.

At Revolution Health, many men choose pellet therapy to address low testosterone symptoms such as fatigue, brain fog, weight gain, decreased libido, muscle loss, and mood changes.

While pellets are safe and effective, it’s important to understand what to expect after insertion, how to care for the site, and when to follow up with labs. This guide will walk you through:

  • Common experiences after a pellet insertion

  • Temporary symptoms that may occur

  • Post-insertion care instructions

  • When to repeat labs and pellets

What Happens After Pellet Insertion?

Pellets are tiny, rice-sized implants placed under the skin (usually in the hip or buttock). After insertion, your body begins to absorb and regulate testosterone from the pellet.

During the first four weeks, your body adjusts to new hormone levels. It’s common to notice temporary changes as your body finds balance.

Common Symptoms After Pellet Insertion

Most men tolerate pellets very well, but some may experience temporary side effects, particularly during their first insertion or in hot, humid weather.

1. Fluid Retention

  • Testosterone stimulates muscle growth and increases water retention.

  • This may cause a temporary weight gain of 2–5 pounds.

  • This effect usually resolves as your body adjusts.

2. Swelling of Hands & Feet

  • Common in hot or humid conditions.

  • Tips to reduce swelling:

    • Drink more water

    • Lower your salt intake

    • Consider cider vinegar capsules (available at most health stores)

    • Contact our office if swelling is bothersome—we may prescribe a mild diuretic

3. Mood Shifts

  • Irritability or mood swings may occur in the early adjustment period, especially if testosterone was very low prior to treatment.

  • These usually disappear once hormones stabilize.

4. Facial Breakouts

  • Testosterone can increase oil production, occasionally leading to acne.

  • Usually resolves within weeks.

  • Managing breakouts:

    • Daily cleansing and use of toner/astringent

    • Contact our office if over-the-counter solutions don’t help

5. Hair Loss

  • Rare, but can occur in men who convert testosterone to DHT (dihydrotestosterone) at higher levels.

  • Adjusting dosage often resolves this.

  • In rare cases, prescription medications may be recommended.

6. Hair Growth

  • Some men notice increased hair growth on the chest, back, abdomen, or arms.

  • This is usually hereditary and dose-related.

  • Adjusting dosage typically reduces or eliminates the issue.

Post-Insertion Care Instructions for Men

Following proper aftercare ensures smooth healing and reduces the chance of complications.

Bandage Care

  • The insertion site is covered with two layers of bandages.

    • Remove the outer pressure bandage after 24 hours (or sooner if wet).

    • The inner layer (waterproof foam tape or steri-strips) should be removed after 3 days.

Activity Guidelines

  • Apply an ice pack to the site for 20 minutes at a time, several times during the first 4–5 hours.

  • Avoid hot tubs, swimming, or tub baths for 3 days.

  • You may shower, but do not scrub the site until healed (about 7 days).

  • Avoid strenuous lower body exercises (running, squats, lunges, elliptical) for 3 days.

Healing Expectations

  • Mild swelling for 1–3 days is normal.

  • The site may feel sore for 2–3 weeks.

  • Bruising or redness may last days to weeks.

  • A small amount of blood on the bandage is common.

  • Apply firm pressure for 5 minutes if bleeding occurs.

When to Call Our Office

  • If bleeding does not stop after applying pressure

  • If you notice pus or abnormal discharge

  • If redness or pain increases significantly

Important Reminders

  • Post-Pellet Labs: Schedule blood work 4 weeks after your pellet insertion so we can evaluate testosterone levels and make adjustments if needed.

  • Repeat Pellet Timing: Most men require pellet re-insertion every 4–5 months.

  • Symptom Monitoring: Schedule a repeat procedure as soon as testosterone-related symptoms begin to return.

Conclusion

Testosterone pellet therapy is one of the most effective ways to restore and maintain optimal hormone levels for men. During the first few weeks, you may notice temporary changes like fluid retention, swelling, or mild acne—but these usually resolve as your body stabilizes.

By following post-care instructions, completing your 4-week labs, and scheduling re-insertions every 4–5 months, you’ll enjoy consistent results and lasting benefits from pellet therapy.

If you experience anything unusual or concerning, contact Revolution Health right away—we’re here to guide you through every step of your hormone optimization journey.