Lp-PLA2, also known as platelet-activating factor acetylhydrolase (PAF-AH), was initially identified as the enzyme responsible for hydrolyzing and inactivating the inflammatory phospholipid PAF (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine).
Apolipoprotein B (apoB) is the major protein component of chylomicrons, very low-density lipoproteins (VLDLs), intermediate-density lipoproteins (IDLs), lipoprotein(a) [Lp(a)], and low-density lipoproteins (LDLs), and constitutes 20-25%...
Lipoprotein(a) [Lp(a)] is a highly heterogeneous molecule, consisting of a low-density lipoprotein (LDL) with a highly glycosylated apolipoprotein(a) [apo(a)] molecule covalently linked to the apolipoprotein...
LDL-cholesterol (LDL-C) lowering by statin therapy has historically been the focus of guidelines for treating cardiovascular disease (CVD) risk associated with elevated blood cholesterol.
For every woman who dies of breast cancer, 8 women will die from cardiovascular disease (heart attacks). We are doing better with identifying and treating...
Plasma fatty acids can be esterified to form triacylglycerols (triglycerides [TGs]) for storage, or metabolized as a high-energy fuel source of adenosine triphosphate (ATP). Plasma...
